Osteonecrosis MCQ | Best MDS Coaching AIPGDEE preparations B-IDS

Drug which can c anrs e the Osteonecrosis of the jaw is ?
A. Corticosteroids
B. Calcitonin
C. Bisphosphonate
D. None

Ans. (C) Ref. http://www.ncbLnlm.nih.gov/pubmed/18022461]

RESULTS: Results in part noted a higher incidence related to alendronate (Fosamax; Merck, Whitehouse Station, NJ), a 94.7% predilection for trre posterior mandible, and a 50% occurrence spontaneously, with the remaining 50% resulting from an oral surgical procedure, mostly tooth removals. Just over 53% of patients were taking their oral bisphosphonate for osteoperua. 33.3% for documented osteoporosis, and 13.4% for steroid-induced osteoporosis related to 4 or more' years of prednisone therapy for an autoimmune condition, There was a direct exponential relationship between the size of the exposed bone and the duration of oral bisphosphonate use There was also a

direct correlation between reports of pain and clinical evidence of infection,